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Resources
Running scripts from Toolbar buttons
This is only for Windows Rhino right now since you can't customize toolbar buttons on Mac yet, but once that feature becomes available I'm pretty sure the technique will be the same. In Rhino, create a new toolbar button and edit it. Consult the Rhino help for for adding and editing toolbar buttons.
stevebaer.wordpress.com
How to Set Up and Run Macros and Scripts in Rhino
The simplest way to save and run your macro is from a toolbar button or alias. If you don't know how to make a new toolbar button or alias, look in the Help file. There's a good explanation. Once you have your new button (or have chosen to edit an existing one), open the editor by shift right-clicking on the button.
wiki.mcneel.com